Further Reading

Friday 15 January 2021

COVID Diagnosis with PCR | Misinterpreting results | Cycle threshold explained



The video above explains how the PCR test works and how we are interpreting results incorrectly. In summary, the PCR swab collects RNA from your nasal cavity. This RNA is then reverse transcribed into DNA. Due to its tiny size, it must be amplified to become discernible. Each round of amplification is called a cycle, and the number of amplification cycles used by any given test or lab is called a cycle threshold (CT). 

 The higher the CT, the greater the risk that insignificant sequences of viral DNA end up being magnified to the point that the test reads positive even if your viral load is extremely low or the virus is inactive and poses no threat to you or anyone else.