Butyrate, a short-chain fatty acid produced when gut bacteria
ferment dietary fibre, serves as both an energy source for colon cells
and an important signalling molecule for immune regulation.
By
inhibiting histone deacetylases (“HDAC”) and suppressing the NF-κB
pathway, butyrate acts as a powerful anti-inflammatory agent, helping
prevent chronic inflammation that contributes to various diseases.
Butyrate
promotes regulatory T cell development while modulating other immune
cells, helping maintain immune tolerance and preventing autoimmune
responses while supporting balanced immune function.
Butyrate
plays a significant role in managing chronic diseases like inflammatory
bowel disease (“IBD”), multiple sclerosis and Type 2 diabetes by
reducing inflammation and supporting gut barrier function.
Emerging
research suggests that butyrate influences brain health by modulating
the gut-brain axis; it reduces neuroinflammation and supports cognitive
function and plays a supporting role in the prevention of neurological
disorders like Alzheimer’s disease and depression....<<<Read More>>>...
