[SOTT]: T-cells from common cold coronaviruses can provide protection against COVID-19, an Imperial College London study has found. Reuters reports on the findings, which were published in Nature.
The study, which began in September 2020, looked at levels of cross-reactive T-cells generated by previous common colds in 52 household contacts of positive COVID-19 cases shortly after exposure, to see if they went on to develop infection.
It found that the 26 who did not develop infection had significantly higher levels of those T-cells than people who did get infected. Imperial did not say how long protection from the T-cells would last.
"We found that high levels of pre-existing T cells, created by the body when infected with other human coronaviruses like the common cold, can protect against COVID-19 infection," study author Dr Rhia Kundu said. The researchers suggest vaccines based on imitating the internal virus proteins that T-cells target may be more resilient to mutations and new variants as those proteins, unlike the spike protein targeted by the current vaccines, "mutate much less".
Cross-immunity to SARS-CoV-2 from other coronaviruses has been proposed since early on in the pandemic as an important element in reaching herd immunity and endemicity (for example, it was mentioned in this Scientist article from March 2020), and became a particular focus of interest in the autumn of 2020 as evidence of it accumulated (see here, here and here). It's good to have further confirmation of this from Imperial (and also recently from UCL), but it has to be said it's pretty late to the party, and it's not clear why a study which began in September 2020 during a public health emergency has taken 16 months to report, particularly when vaccines were brought to market in 10 months. The emphasis of the researchers is on the potential usefulness of the findings for developing new and more resilient vaccines, which contains a tacit admission that the existing vaccines are failing, but also leaves one wondering whether the research has only been published now that it is useful for making new pharmaceutical products. It might be added that the studies on the efficacy of generic off-label medicines against Covid are taking an awfully long time to report.
As Dr. Mike Yeadon explained in his October 2020 piece for the Daily Sceptic, "What SAGE Has Got Wrong", the assumption of a lack of pre-existing immunity and hence universal susceptibility was one of the great errors made by Government advisers throughout the pandemic and which led to an over-reaction that continues to this day. Now that Imperial researchers have acknowledged the existence of prior immunity, will Neil Ferguson's modelling team update its assumptions? ...<<<Read More>>>...
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Showing posts with label Natural Immunity. Show all posts
Showing posts with label Natural Immunity. Show all posts
Thursday, 13 January 2022
Sunday, 24 October 2021
Antibacterial Agents ( ‘AncientBiotics’ ) From Nature
[Wake Up World]: With antimicrobial-resistant infections on the rise, scientists are now looking with interest at ancient medieval medical texts, which include various recipes to treat conditions that were likely microbial infections and/or cases of dysbios where certain naturally occurring microbes grew opportunistically and out of proportion to its natural ratios. One such remedy that’s 1,000 years old included crushed garlic and a second substance in the Allium species combined with wine and oxgall, or bovine bile, then left to sit in a brass or bronze vessel for nine days and nights.
“The ingredients combined to treat this infection appear promising to the modern microbiologist,” researchers wrote in the journal mBio. They reconstructed the remedy, which they believe was used to treat styes, then known as “wen,” which are caused by Staphylococcus aureus bacteria.
The “ancientbiotics” turned out to be effective, with the study noting their “activity relies on the combined activity of several antimicrobial ingredients” and highlights the “untapped potential of premodern remedies for yielding novel therapeutics at a time when new antibiotics are desperately needed.” In other instances, garlic was used by ancient Greece, Rome, India and China for infections and respiratory ailments, while in ancient Egypt, China, Serbia, Greece and Rome moldy bread was applied as a topical treatment for infections. Other ancient civilizations relied on herbs, honey and, in some cases, animal feces to treat infection...<<<Read More>>>...
“The ingredients combined to treat this infection appear promising to the modern microbiologist,” researchers wrote in the journal mBio. They reconstructed the remedy, which they believe was used to treat styes, then known as “wen,” which are caused by Staphylococcus aureus bacteria.
The “ancientbiotics” turned out to be effective, with the study noting their “activity relies on the combined activity of several antimicrobial ingredients” and highlights the “untapped potential of premodern remedies for yielding novel therapeutics at a time when new antibiotics are desperately needed.” In other instances, garlic was used by ancient Greece, Rome, India and China for infections and respiratory ailments, while in ancient Egypt, China, Serbia, Greece and Rome moldy bread was applied as a topical treatment for infections. Other ancient civilizations relied on herbs, honey and, in some cases, animal feces to treat infection...<<<Read More>>>...
Friday, 17 September 2021
CDC admits natural immunity offers better protection than experimental COVID jabs
[Natural News]: The CDC is admitting natural immunity provides better protection against Covid-19 than the experimental jabs just a week after Dr. Anthony Fauci failed to explain why a person who recovered from Covid should still get the vaccine.
Dr. Sanjay Gupta asked Fauci last week about an Israeli study showing natural immunity provides better protection against Covid variants than Covid vaccines.
“What are people to make of that?” Gupta asked. “I get calls all the time, people say, ‘I’ve already had Covid, I’m protected.’ And now, this study says maybe even more protected than the vaccine alone. Should they also get the vaccine? How do you make the case to them?”
“That’s a really good point Sanjay, I don’t have a really firm answer for you on that,” Fauci said, adding, “What the paper from Israel didn’t tell you is whether or not, as high as the protection is with natural infection, what’s the durability compared to the durability of a vaccine?”...<<<Read More>>>...
Dr. Sanjay Gupta asked Fauci last week about an Israeli study showing natural immunity provides better protection against Covid variants than Covid vaccines.
“What are people to make of that?” Gupta asked. “I get calls all the time, people say, ‘I’ve already had Covid, I’m protected.’ And now, this study says maybe even more protected than the vaccine alone. Should they also get the vaccine? How do you make the case to them?”
“That’s a really good point Sanjay, I don’t have a really firm answer for you on that,” Fauci said, adding, “What the paper from Israel didn’t tell you is whether or not, as high as the protection is with natural infection, what’s the durability compared to the durability of a vaccine?”...<<<Read More>>>...
Thursday, 9 September 2021
Why Isn’t Anyone Talking About Natural Immunity?
{Humans Are Free]: individuals are blaming the unvaccinated for absolutely everything going wrong these days. There is a long, detailed history of the “othering” of a population leading to all sorts of horrors.
However, it is wrong at a more mundane level, as well. Public discourse surrounding the pandemic seems to focus solely on vaccination as a means of achieving herd immunity. Those who have recovered from the disease and have natural immunity, are being completely ignored.
But why?
Our innate defenses are things like our skin and mucus. We’re born with these, and they make it difficult for various pathogens such as bacteria, viruses, and multicellular parasites to enter our bodies. Our bodies also have an immune system that recognizes and attacks any infectious agents that make it past our innate defenses.
Our immune system is really sophisticated, and in healthy individuals, it works pretty well. Suppose some kind of pathogen makes it past the body’s innate defenses and begins infecting cells within the host. In that case, the host’s body will, in turn, start producing antibodies that will specifically attack the invading pathogen. The host body will continue producing antibodies until either the host dies or the invading cells die, and the patient’s body can return to normal.
The best part is, even after the active infection is over, the host’s body will retain the memory of the antibodies it produced during the infection. So if the formerly infected person reencounters the pathogen, the body will immediately have the antibodies to kill the pathogen. They rarely get sick again, and if they do, it’s generally very mild....<<<Read More>>>...
However, it is wrong at a more mundane level, as well. Public discourse surrounding the pandemic seems to focus solely on vaccination as a means of achieving herd immunity. Those who have recovered from the disease and have natural immunity, are being completely ignored.
But why?
Our innate defenses are things like our skin and mucus. We’re born with these, and they make it difficult for various pathogens such as bacteria, viruses, and multicellular parasites to enter our bodies. Our bodies also have an immune system that recognizes and attacks any infectious agents that make it past our innate defenses.
Our immune system is really sophisticated, and in healthy individuals, it works pretty well. Suppose some kind of pathogen makes it past the body’s innate defenses and begins infecting cells within the host. In that case, the host’s body will, in turn, start producing antibodies that will specifically attack the invading pathogen. The host body will continue producing antibodies until either the host dies or the invading cells die, and the patient’s body can return to normal.
The best part is, even after the active infection is over, the host’s body will retain the memory of the antibodies it produced during the infection. So if the formerly infected person reencounters the pathogen, the body will immediately have the antibodies to kill the pathogen. They rarely get sick again, and if they do, it’s generally very mild....<<<Read More>>>...
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