S.O.T.T: No one will argue the fact that heroin, morphine, and pain killers are highly addictive substances. They become addictive due to their ability to suppress pain, reduce anxiety, and can even cause us to have a higher sense of joy. There is another opiate that most of us consume on a daily basis that may be just as addicting, and that is sugar. Opioid receptors are located in the brain and the spinal column. They are 7 transmembrane-spanning, G protein-coupled receptors. They are responsible for aiding neurotransmitters and hormones, the most well known being our endorphins. Addictive substances work by enacting upon these receptor sites (Waldhoer, 2004). To further understand this, let us look at heroin addiction. Basically, heroin increases the amount of dopamine. Dopamine is the neurotransmitter responsible for energy, memory, and focus. Our system has a checks and balances process. When dopamine is released, we also release GABA to counteract it. The problem with heroin is it enacts upon the opioid receptor responsible for GABA. This disallows GABA to do its job. We are then left with a dopamine surge left unbalanced
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