VEXAS syndrome, short for vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome, is said to be caused by mutations in the innate immune cells, as well as a somatic mutation in the UBA1 gene found on the X chromosome. Most inflammatory diseases, by the way, are caused by dysfunction that arises in adaptive immune cells.
"Somatic mutations cannot be inherited, meaning individuals acquire this mutation later in life," explains The Epoch Times about the disease. "The mutation affects the stem cells in the bone marrow. The cells mature into specialized immune cells that circulate within the bloodstream."
"Immune cells carrying the UBA1 mutation are highly inflammatory, and once enough of them accumulate, patients start developing symptoms."...<<<Read More>>>....
