Belgian Police say the DNA found on the bottle was that of a man not a girl.
Sky News correspondent Greg Milam, who is in Belgium, said that the inconclusive nature of the result means police are still desperate to trace the couple and the youngster and have not yet ruled out the possibility that it is Madeleine. "There has been huge publicity here and yet they have still not come forward and their car, which had Begian number plates, hasn't been traced," he said.
In a radio interview Madeleine's mother, Kate McCann, said that although there was no positive news she was encouraged that people were still looking for her daughter.
"It says to us that people are still looking and that is really important and we would encourage that," she said. "I probably have more hope now than I did at the beginning."
She added: "We haven't had any news to the contrary that Madeleine isn't alive, and that's very important."